Dubai PR Network, Online Press Release from Dubai and Middle East
 
Healthcare(Healthcare & Medicine)
Filter PR by
  
New Targeted Gene Therapy Could Keep Lung Cancer from Progressing Thereby Extending and Improving Lives of Millions of Patients Worldwide
 

In a clinical trial, 81 percent of lung cancer patients experience disease control, says expert from American hospital Cleveland Clinic
 
  
July 31, 2021:   newly targeted therapy could help millions of lung cancer patients worldwide keep their cancers from spreading, says an expert at a top American hospital, Cleveland Clinic, ahead of World Lung Cancer Day on August 1.

Dr. Khaled Hassan, of the Hematology and Medical Oncology Department at Cleveland Clinic, said: “The KRAS mutation is a main gene that drives cancer, and lung cancer specifically, but previously it’s been difficult to target. With the new KRAS targeted therapy, 81 percent of cancer patients kept their cancer under control, which could extend and improve patients’ lives by about six months. One third of the patients had an objective response rate, of shrinking and/or totally eliminating cancer, even though previous chemotherapy failed to control their disease. We now have targeted therapies for eight cancer-driving genes, and patients are responding very well.”
 
In the clinical trial - of which Dr. Hassan was not a part - about four out of five (81 percent) patients achieved disease control, meaning the cancer disappeared, went into remission, or stayed the same. About one third of total patients (36 percent) achieved an objective response rate, meaning the cancer shrunk or disappeared completely.
 
Worldwide, lung cancer is the second most common type of cancer, with 2.21 million new cases in 2020, and the leading cause of cancer death, at 1.8 million deaths in 2020, according to the World Health Organization.
 
The US Food and Drug Administration recently approved the use of a new targeted therapy for cancer tumors with the KRAS G12C mutation. The KRAS mutation accounts for approximately 25 percent of mutations in non-small cell lung cancers, and the G12C mutation represents about 13 percent of mutations in non-small cell lung cancers.
 
 
“Targeted therapies are designed to be very selective to bind to the pathways of specific gene mutations, and can get rid of most of the toxicities in the cancer cells with only minor side effects,” added Dr. Hassan, who said that Cleveland Clinic is already prescribing the treatment to patients. “For the remaining patients who did not respond to this targeted therapy, we need to figure out how to develop drugs that can target the genes’ pathway to resistance.”
 
However, Dr. Hassan cautioned that this KRAS targeted therapy is not a cure, as eventually the cancer cells can find a way around the treatment and develop resistance.
 
Dr. Hassan concluded: “As we mark World Lung Cancer Day, the two most important points are for patients to stop smoking, which can cause cancer and other diseases, and for those who are high risk to get early, safe low-dose CT scan screenings. The highest risk patients are 50 years or older, and have smoked at least one pack of cigarettes a day for 20 years.”
 

Posted by : Dubai PR Network Editorial Team
Viewed 6234 times
PR Category : Healthcare & Medicine
Posted on : Saturday, July 31, 2021  12:40:00 PM UAE local time (GMT+4)
Replication or redistribution in whole or in part is expressly prohibited without the prior written consent of DubaiPRNetwork.com.
Previous Story : On the French National Day, Ambassador of France to the UAE ...
Next Story : Over 300 Aster Doctors honoured with UAE's Golden Visa
Email this article Print this article

Share this article with your friends and followers
NewsVine
Back to Section Home

Related Stories



 
 
Most Viewed Press Release posted in the last 7 days
More Than Half of UAE Residents Affected by Heart Disease [12763-Views]
Ministry of Health marks World Patient Safety Day 2021 [12599-Views]
Major Saudi Aerospace Players to take part at Dubai Airshow 2021 [12484-Views]
Ogilvy Names Ben Messiaen Chief Client Officer for EMEA [6736-Views]
Louis Moinet Moon Race - A Journey through Space [4694-Views]
Etihad Stuns Visitors to Mall of the Emirates With 50% Flight Discounts [3792-Views]
UAE Residents, Visitors and Saudi Citizens Come Together to Celebrate 91st KSA National Da... [3633-Views]
Gastech 2021 Exhibition and Conference Opens as Global Energy Industry Gathers to Set [3268-Views]
Oris Big Crown ProPilot Rega Fleet Limited Edition [3177-Views]
SEHA Integrates UAE Pass With Its Mobile App and Patient Portal [3079-Views]
2021 Green Good DesignTM Award [3018-Views]
Sharjah International Award for Refugee Advocacy and Support Calls for Nominations for 202... [2886-Views]
Fall in Love with THAT Concept Store's Fall-Winter Collection [2825-Views]
Majid Al Futtaim to Hire 3000 Emiratis In response to “NAFIS” [2788-Views]
Gulf Youth Sport Expo to Bring Together Leading Industry Experts for Discussions and Netwo... [2767-Views]
Jaguar Land Rover to Provide Fleet of All Electric Vehicles for World Leaders at Cop26 [2751-Views]
Peter Rabbit Adventure Zone Hops into Global Village [2677-Views]
Hyundai Motor Presents Carbon Neutral Commitment at IAA Mobility 2021 [2558-Views]
Guinness World Records 2022 Discover Your World [2522-Views]
Hirschi Takes Win and Race Lead in Luxembourg [2415-Views]
Abu Dhabi University holds Virtual Graduation Ceremony for 2021 Cohort [2345-Views]
Combat Dull Skin & Glow From Within! [2333-Views]
Guinness World Records Verifies Oldest Identical Twins Ever [2222-Views]
Hitachi ABB Power Grids to Supply Step-up Transformers for World's Largest Single-site Sol... [2136-Views]
Dubai Municipality Wins 10 Categories of International Stevie Awards [2132-Views]
 
RSS Facebook Twitter LinkedDin DubaiPRNetwork.com on Instagram
 
Top Sections
 
Top Stories